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DuP 105

CAS No. : 96800-41-8

MCE 国际站：DuP 105

产品活性：DuP 105 是一种可口服的恶唑烷酮类化合物，能够抗葛兰素阳性菌。

研究领域：Anti-infection

作用靶点：Bacterial  |  Antibiotic

In Vitro: DuP 105 shows inhibitory activities against staphylococcal isolates and B. fragilis isolates with MIC₉₀s of 4 to 16 μg/mL and 16 μg/mL. DuP 105 MICs for 50% of the 216 gram-positive isolates tested (MIC₅₀s) range from 4.0 to 16 μg/mL.

In Vivo: DuP 105 administered by either the oral or the parenteral route is protective against staphylococcal and streptococcal infections in mice with the 50% effective doses of 9 to 23 mg/kg.

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