Human ANGPTL4 ELISA Kit (Sandwich ELISA) - LS-F24356

价格： $690

品牌：LSBio

货号：LS-F24356

产品详情

Human ANGPTL4 ELISA Kit (Sandwich ELISA) - LS-F24356

Catalog Number:	LS-F24356
Type:	Sandwich ELISA (enzyme-linked immunosorbent assay) kit
Target:	ANGPTL4
Reactivity:	Human
Specificity:	For the detection and quantification of endogenous levels of natural and/or recombinant Human ANGPTL4 proteins.
Description:	LS-F24356 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Human ANGPTL4 in samples of Cell Culture Supernatants, Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of ANGPTL4 as low as 600 picograms per milliliter.

Intended Sample Types:

Cell Culture Supernatants, Plasma, Serum

Format:	96-Well Strip Plate
Detection:	Colorimetric - 450nm (TMB)
Measurement:	Quantitative
Detection Range:	1250 - 80000 pg/ml
Sensitivity:	600 pg/ml

Quality Assurance:

Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.

Kit Components:

Coated 96-well Strip Plate
Standard (Lyophilized)
Biotinylated Detection Antibody (100x)
HRP-Streptavidin Conjugate (100x)
Sample Diluent
Biotinylated Detection Antibody Diluent
HRP-Streptavidin Conjugate Diluent
Wash Buffer (20x)
TMB Substrate
Stop Solution
Adhesive Plate Sealers

Background:

Angiopoietin-related protein 4 (Angptl4) is a protein that in humans is encoded by the ANGPTL4 gene. This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. By radiation hybrid analysis, Angptl4 gene is mapped to 19p13.3. ANGPTL4 contributed to tumor growth and protected cells from anoikis, a form of programmed cell death induced when contact-dependent cells detach from the surrounding tissue matrix.

Storage:	Short term: 4°C; Long term: see manual.
Restrictions:	For research use only.

About ANGPTL4

Uniprot: Q9BY76 NCBI: AF202636 AAG22490.1

Synonyms: ANGPTL4 ElisaKit, Angiopoietin-like 4 ElisaKit, Angiopoietin-related protein 4 ElisaKit, Angiopoietin-like protein 4 ElisaKit, Fasting-induced adipose factor ElisaKit, NL2 ElisaKit, PGAR ElisaKit, Pp1158 ElisaKit, ARP4 ElisaKit, FIAF ElisaKit, HFARP ElisaKit

Description: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity.
(More About ANGPTL4)
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