Nogo R轴索过度生长抑制因子受体/Nogo受体抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

目录编号 ：LM-20486R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Nogo R

抗体名 ：轴索过度生长抑制因子受体/Nogo受体抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat,

免疫原 ：KLH conjugated synthetic peptide derived from human Nogo R:331-430/473

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）

浓度 ：1mg/ml

保存条件 ：Store at -20 °C

规格 ：100ul  200ul

Nogo R轴索过度生长抑制因子受体/Nogo受体抗体

英文名称	Nogo R
中文名称	轴索过度生长抑制因子受体/Nogo受体抗体
别    名	NgR; Nogo-66 receptor; Nogor; NogoR; Nogo-R; Reticulon 4 receptor; Rtn4r; RTN4R_HUMAN.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	细胞生物  神经生物学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,
产品应用	WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	48kDa
细胞定位	细胞膜
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human Nogo R:331-430/473
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord. Function: Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity). Subunit: Homomultimer. Interacts with LINGO1. Interacts with KIAA0319L. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Similarity: Belongs to the Nogo receptor family.  Contains 8 LRR (leucine-rich) repeats.  Contains 1 LRRCT domain.  Contains 1 LRRNT domain. SWISS: Q9BZR6 Gene ID: 65078 Database links: Entrez Gene: 65078 Human Entrez Gene: 65079 Mouse Entrez Gene: 113912 Rat Omim: 605566 Human SwissProt: Q9BZR6 Human SwissProt: Q99PI8 Mouse SwissProt: Q99M75 Rat Unigene: 30868 Human Unigene: 40149 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample:Cerebrum (Mouse)Lysate at 40 ug Primary: Anti-Nogo R(bs-20486R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 48kD Sample:Heart(Mouse)Lysate at 40 ug Primary: Anti-Nogo R(bs-20486R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 48kD