NRG2神经调节蛋白2抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

目录编号 ：LM-19347R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：NRG2

抗体名 ：神经调节蛋白2抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat,

免疫原 ：KLH conjugated synthetic peptide derived from human NRG2:341-440/850 <Extracellular>

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

浓度 ：1mg/ml

保存条件 ：Store at -20 °C

规格 ：100ul  200ul

NRG2神经调节蛋白2抗体

英文名称	NRG2
中文名称	神经调节蛋白2抗体
别    名	Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2_HUMAN; NTAK; Pro NRG2; Pro-NRG2.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	细胞生物  神经生物学  信号转导  生长因子和激素
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,
产品应用	ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	82kDa
细胞定位	细胞膜 分泌型蛋白
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human NRG2:341-440/850 <Extracellular>
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010] Function: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor. Subcellular Location: Secreted and Cell membrane. Does not seem to be active. Tissue Specificity: Restricted to the cerebellum in the adult. Post-translational modifications: Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form. Extensive glycosylation precedes the proteolytic cleavage. Similarity: Belongs to the neuregulin family. Contains 1 EGF-like domain. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. SWISS: O14511 Gene ID: 9542 Database links: Entrez Gene: 9542 Human Entrez Gene: 100042150 Mouse Entrez Gene: 432361 Rat Omim: 603818 Human SwissProt: O14511 Human SwissProt: P56974 Mouse SwissProt: O35569 Rat Unigene: 408515 Human Unigene: 380390 Mouse Unigene: 22434 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.