SPCS3信号肽复合物亚基3抗体价格_品牌:LMAI Bio-丁香通官网

供应商：上海联迈生物工程有限公司

库存：大量

目录编号：LM-17643R

克隆性：多克隆

抗原来源：Rabbit

保质期：1年

抗体英文名：SPCS3

抗体名：信号肽复合物亚基3抗体

宿主：Rabbit

适应物种：Human, Mouse, Rat, Cow, Horse,

免疫原：KLH conjugated synthetic peptide derived from human SPCS3:51-120/180

亚型：IgG

形态：Lyophilized or Liquid

应用范围：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

浓度：1mg/ml

保存条件：Store at -20 °C

规格：100ul 200ul

SPCS3信号肽复合物亚基3抗体

英文名称	SPCS3
中文名称	信号肽复合物亚基3抗体
别名	DKFZp564J1864; FLJ22649; Microsomal signal peptidase 22/23 kDa subunit; Microsomal signal peptidase 23 kDa subunit; PRO3567; Signal peptidase complex subunit 3; Signal peptidase complex subunit 3 homolog (S. cerevisiae); Signal peptidase complex subunit 3 homolog; SPase 22 kDa subunit; SPase 22/23 kDa subunit; SPC22; SPC22/23; SPC3; UNQ1841; YLR066W.
规格价格	100ul/1380元购买 200ul/2200元购买大包装/询价
说明书	100ul 200ul
研究领域	细胞生物信号转导表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Cow, Horse,
产品应用	ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	20kDa
细胞定位	细胞浆
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human SPCS3:51-120/180
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: SPCS3 (signal peptidase complex subunit 3), also known as SPC3, is a 180 amino acid single-pass type II membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER) and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS3 functions to remove signal peptides from proteins that are translated to the lumen of the ER. The gene encoding SPCS3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: A component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Subunit: Component of the microsomal signal peptidase complex which consists of five members: SEC11A, SEC11C, SPCS1, SPCS2 and SPCS3. Subcellular Location: Endoplasmic reticulum and Microsome membrane;: Single-pass type II membrane protein Similarity: Belongs to the SPCS3 family. SWISS: P61009 Gene ID: 60559 Database links: Entrez Gene: 767917 Cow Entrez Gene: 404005 Dog Entrez Gene: 60559 Human Entrez Gene: 76219 Mouse Entrez Gene: 76976 Mouse Entrez Gene: 100360464 Rat Entrez Gene: 317409 Rat SwissProt: Q3SZU5 Cow SwissProt: P61008 Dog SwissProt: P61009 Human SwissProt: Q9D365 Mouse SwissProt: Q568Z4 Rat Unigene: 6322 Cow Unigene: 3875 Dog Unigene: 42194 Human Unigene: 328305 Mouse Unigene: 482965 Mouse Unigene: 162344 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SPCS3) Polyclonal Antibody, Unconjugated (bs-17643R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.