SPCS2信号肽复合物亚基2抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

目录编号 ：LM-17641R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：SPCS2

抗体名 ：信号肽复合物亚基2抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, 

免疫原 ：KLH conjugated synthetic peptide derived from human SPCS2:2-100/226 <Cytoplasmic>

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

浓度 ：1mg/ml

保存条件 ：Store at -20 °C

规格 ：100ul  200ul

SPCS2信号肽复合物亚基2抗体

英文名称	SPCS2
中文名称	信号肽复合物亚基2抗体
别    名	Microsomal signal peptidase 25 kDa subunit; Signal peptidase complex subunit 2; Signal peptidase complex subunit 2 homolog (S. cerevisiae); SPase 25 kDa subunit; SPCS2; SPCS2_HUMAN.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	细胞生物  免疫学  信号转导
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	25kDa
细胞定位	细胞膜
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human SPCS2:2-100/226 <Cytoplasmic>
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Subunit: Component of the microsomal signal peptidase complex which consists of five members: SEC11A, SEC11C, SPCS1, SPCS2 and SPCS3.  Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Similarity: Belongs to the SPCS2 family. SWISS: Q15005 Gene ID: 9789 Database links: Entrez Gene: 9789 Human Entrez Gene: 66624 Mouse Entrez Gene: 293142 Rat SwissProt: Q15005 Human SwissProt: Q9CYN2 Mouse Unigene: 282700 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.