FAM76B antibody

供应商 ：上海康朗生物科技有限公司

库存 ：大量

目录编号 ：kl-9659R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：12个月

抗体英文名 ：FAM76B antibody

抗体名 ：FAM76B蛋白抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,

免疫原 ：KLH conjugated synthetic peptide derived from human FAM76B:251-339/339

亚型 ：IgG

形态 ：冻干粉或液体

应用范围 ：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul 200ul

FAM76B antibody

中文名称	FAM76B蛋白抗体
别    名	Family with sequence similarity 76 member B; Hypothetical protein LOC143684; MGC33371; FA76B_HUMAN.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	心血管  细胞生物  发育生物学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	39kDa
细胞定位	细胞核
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human FAM76B:251-339/339
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The FAM76B gene product has been provisionally designated FAM76B pending further characterization. Subcellular Location: Nucleus speckle.  Post-translational modifications: Isoform 2 is ubiquitinated at Lys-225.  Phosphorylated upon DNA damage, probably by ATM or ATR.  Similarity: Belongs to the FAM76 family. SWISS: Q5HYJ3  Gene ID: 143684 Database links: Entrez Gene: 143684 Human Entrez Gene: 72826 Mouse Entrez Gene: 367021 Rat SwissProt: Q5HYJ3 Human SwissProt: Q80XP8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti-FAM76B (bs-9659R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 39 kD Observed band size: 39 kD