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保存条件 :Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
库存 :货期:1-2天
供应商 :MedChemExpress LLC
CAS号 :179068-02-1
规格 :10 mM * 1 mL/2 mg/5 mg/10 mg/25 mg/50 mg/100 mg
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PHCCC
CAS No. : 179068-02-1
MCE 国际站:PHCCC
产品活性:PHCCC 是一种 I 型 mGluR (Group I mGluR) 拮抗剂,IC50 为 3 μM,PHCCC 也是 mGlu4 受体选择性正向调节剂。具有抗帕金森病作用。
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:mGluR
In Vitro: PHCCC potentiated the effect of L-(+)-2-amino-4-phosphonobutyric acid (L-AP4) in inhibiting transmission at the striatopallidal synapse.
In Vivo: PHCCC (75 nmol/2.5 μl; intracerebroventricular) produces an antiparkinsonian effect in a dopamine depletion akinesia model.
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