IGSF8 antibody

供应商 ：上海康朗生物科技有限公司

库存 ：大量

目录编号 ：kl-2584R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：12个月

抗体英文名 ：IGSF8 antibody

抗体名 ：免疫球蛋超家族成员8抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat, Pig, Cow, Horse,

免疫原 ：KLH conjugated synthetic peptide derived from mouse IGSF8:101-200/611 <Extracellular>

亚型 ：IgG

形态 ：冻干粉或液体

应用范围 ：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test IF=1:100-500

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul 200ul

IGSF8 antibody

中文名称	免疫球蛋超家族成员8抗体
别    名	CD316; CD316 antigen; CD81 partner 3; CD81P3; EWI-2; EWI2; Glu-Trp-Ile EWI motif-containing protein 2; igsf-8; IgSF8; IGSF8_MOUSE; Immunoglobulin superfamily member 8; Immunoglobulin superfamily member 8 precursor; KCT-4; KCT4; Keratinocytes-associated transmembrane protein 4; LIR-D1; PGRL; Prostaglandin regulatory-like protein.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	肿瘤  细胞生物  免疫学  微生物学  细菌及病毒
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Pig, Cow, Horse,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	62kDa
细胞定位	细胞膜
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from mouse IGSF8:101-200/611 <Extracellular>
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: IGSF8 is a 65kDa single-pass membrane protein that may play a key role in many of the functions attributed to CD81 and CD9, like Hepatitis C infection and oocyte fertilization. It is also believed that this protein acts as a negative regulator of cell motility (e.g. T-cell mobility, prostate cancer cell migration) and is involved in the regulation of neurite outgrowth and maintenance of the neural network in the brain. Function: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. Subunit: Interacts directly with CD82 and CD9/tetraspanin-29. Also interacts with integrin alpha-3/beta-1 and integrin alpha-4/beta-1. Interacts with CD81/tetraspanin-28.  Subcellular Location: Cell membrane; Single-pass membrane protein.  Tissue Specificity: Expressed in lymphocytes as well as in many tissues with higher expression in brain. Detected in all regions of the brain with weak expression in the pituitary. Expressed selectively by neurons but not by glial cells. Similarity: Contains 4 Ig-like C2-type (immunoglobulin-like) domains. SWISS: Q8R366 Gene ID: 140559 Database links: Entrez Gene: 93185 Human Entrez Gene: 140559 Mouse Omim: 606644 Human SwissProt: Q969P0 Human SwissProt: Q8R366 Mouse Unigene: 332012 Human Unigene: 271717 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample: Brain(Mouse) lysate at 30ug;  Primary: Anti-IGSF8 (bs-2584R) at 1:300 dilution;  Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution ;  Predicted band size: 62 kD Observed band size: 55 kD Blank control(blue):Raji (fixed with 2% paraformaldehyde (10 min)).  Primary Antibody:Rabbit Anti-IGSF8 antibody(bs-2584R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;  Isotype Control Antibody: Rabbit IgG(orange), used under the same conditions );  Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.