TM2D1 antibody

供应商 ：上海康朗生物科技有限公司

库存 ：大量

目录编号 ：kl-19942R

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：12个月

抗体英文名 ：TM2D1 antibody

抗体名 ：β淀粉样蛋白结合蛋白抗体

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

免疫原 ：KLH conjugated synthetic peptide derived from human TM2D1:38-100/207 

亚型 ：IgG

形态 ：冻干粉或液体

应用范围 ：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul 200ul

TM2D1 antibody

中文名称	β淀粉样蛋白结合蛋白抗体
别    名	BBP; Beta amyloid binding protein; hBBP; TM2 domain containing 1; TM2 domain containing protein 1; TM2D1.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	细胞生物  神经生物学  信号转导  细胞凋亡  Alzheimer's
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用	ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	19kDa
细胞定位	细胞膜
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human TM2D1:38-100/207
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq, Dec 2008] Function: May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42. Subunit: Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed. Post-translational modifications: N-glycosylated. Similarity: Belongs to the TM2 family. SWISS: Q9BX74 Gene ID: 83941 Database links: Entrez Gene: 83941 Human Entrez Gene: 94043 Mouse Entrez Gene: 362545 Rat Omim: 610080 Human SwissProt: Q9BX74 Human SwissProt: Q99MB3 Mouse Unigene: 656790 Human Unigene: 331719 Mouse Unigene: 198278 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.