Recombinant Murine TPO

库存 ：大量

英文名 ：Recombinant Murine TPO

保质期 ：一年

供应商 ：上海联迈生物工程有限公司

保存条件 ：-20℃或更低温度保存

规格 ：2μg

Recombinant Murine TPO

产品编号	产品名称	产品包装	产品价格
LM6011-2μg	Recombinant Murine TPO	2μg	464.00元

 

Species	Gene ID	Accession	Source	Length	MW	Tag
Mouse	21832	LM40226	E. coli	174aa	18.7kDa	－

 

About this Antibody
Name	Recombinant Murine TPO (Recombinant Murine Thrombopoietin; rMuTPO)；Recombinant Mouse TPO ; 重组小鼠促血小板生成素
Synonyms	MGDF; MK-CSF; THPO; Tpo; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDFC-mpl ligand; ML; MPL ligand; MPLLGMGC163194; Myeloproliferative leukemia virus oncogene ligand; thrombopoietin; thrombopoietin nirs variant 1; TPOMKCSF
Purity	>95% by SDS-PAGE and HPLC analyses.
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0ng/ml, corresponding to a specific activity of >1.0×106IU/mg.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 5% Trehalose.
Endotoxin	Less than 0.1EU/μg of rMuTPO as determined by LAL method.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Category	Cytokine
Background	Thrombopoietin (TPO), the ligand for the receptor encoded by the c-Mpl proto-oncogene, is a key regulator of megakaryocytopoiesis and thrombopoiesis in vitro and in vivo. The cDNAs for TPO have recently been cloned from canine, murine and human sources. The proteins from these three species are highly conserved, exhibiting from 69-75% sequence identity at the amino acid level. Two distinct domains, separated by a pair of arginine residues that may be a proteolytic cleavage site, have been identified in TPO: the amino terminal region exhibiting sequence homology to erythropoietin and the carboxy terminal region containing multiple potential N-linked glycosylation sites. Recombinant TPO has now been shown to stimulate the maturation, as well as the proliferation, of megakaryocytes and may have important therapeutic applications for the treatment of various clinical conditions associated with thrombocytopenia.
Amino Acid Sequence	SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF

包装清单:

产品编号	产品名称	包装
LM6011-2μg	Recombinant Murine TPO	2μg
LM6011-10μg	Recombinant Murine TPO	10μg
LM6011-100μg	Recombinant Murine TPO	100μg
LM6011-1mg	Recombinant Murine TPO	1mg
-	说明书	1份

保存条件:
       -20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
       为了您的安全和健康，请穿实验服并戴一次性手套操作。