TAOK3 / JIK Antibody (Internal) | LBP85284 | Leading Biology

保存条件 ：存储在2 - 8°C 2周，长期存储-20°C,防止冻融循环。

英文名 ：TAOK3 / JIK Antibody (Internal)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：50 μg

商品分类：多克隆抗体

产品概述：Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

靶点/蛋白：Human TAOK3.

来源：Goat

参考文献：Tassi E.,et al.J. Biol. Chem. 274:33287-33295(1999).Zhang W.,et al.Biochem. Biophys. Res. Commun. 274:872-879(2000).Yustein J.T.,et al.Oncogene 22:6129-6141(2003).Carter T.G.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

特异性：Human, Rabbit, Pig, Horse, Bovine

别名：Serine/threonine-protein kinase TAO3, 2.7.11.1, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, hKFC-A, Thousand and one amino acid protein 3, TAOK3, DPK, JIK, KDS, MAP3K18

应用：ELISA (1:32000), IHC-P (2-3 μg/ml), WB (1:32000)

简单描述：Goat Polyclonal TAOK3 / JIK Antibody (Internal). Validated for use in WB, IHC-P, E.

详情：FunctionSerine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).Cellular_LocationCytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membraneTissue_LocationUbiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层