DOCK2 Antibody (C-term) | LBP82543 | Leading Biology

保存条件 ：存储在2 - 8°C 2周，长期存储-20°C,防止冻融循环。

英文名 ：DOCK2 Antibody (C-term)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：400 μl

商品分类：多克隆抗体

产品概述：Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

靶点/蛋白：This DOCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1812-1846 amino acids from the C-terminal region of human DOCK2.

来源：Rabbit

存储溶液：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

参考文献：Nagase T.,et al.DNA Res. 3:321-329(1996).Nishihara H.,et al.Biochim. Biophys. Acta 1452:179-187(1999).Nishihara H.,et al.Blood 100:3968-3974(2002).Nishihara H.,et al.Biochem. Biophys. Res. Commun. 296:716-720(2002).Cote J.-F.,et al.J. Cell Sci. 115:4901-4913(2002).

特异性：Human

别名：Dedicator of cytokinesis protein 2, DOCK2, KIAA0209

应用：WB~~1:1000-1:2000

简单描述：Rabbit polyclonal DOCK2 Antibody (C-term). Validated for use in WB, E.

详情：FunctionInvolved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.Cellular_LocationEndomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actinTissue_LocationSpecifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层