(Mouse) Sox17 Antibody (C-term) | LBP81545 | Leading Biology

保存条件 ：存储在2 - 8°C 2周，长期存储-20°C,防止冻融循环。

英文名 ：(Mouse) Sox17 Antibody (C-term)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：400 μl

商品分类：多克隆抗体

产品概述：Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

靶点/蛋白：This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17.

来源：Rabbit

存储溶液：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

参考文献：Kanai Y.,et al.J. Cell Biol. 133:667-681(1996).Carninci P.,et al.Science 309:1559-1563(2005).Layfield R.,et al.Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.Kanai-Azuma M.,et al.Development 129:2367-2379(2002).Kim I.,et al.Cell 130:470-483(2007).

特异性：Human, Mouse

别名：Transcription factor SOX-17, Sox17, Sox-17

应用：WB~~1:1000

简单描述：Rabbit Polyclonal (Mouse) Sox17 Antibody (C-term). Validated for use in WB, E.

详情：FunctionActs as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.Cellular_LocationNucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:20802155}Tissue_LocationTestis. Detected in lung.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层