GDF9 / GDF-9 Antibody (aa45-59) | LBP64773 | Leading Biology

保存条件 ：Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

英文名 ：GDF9 / GDF-9 Antibody (aa45-59)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：50 μg

商品分类：多克隆抗体

产品概述：Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

靶点/蛋白：Amino acids 45 to 59 of human GDF9

来源：Rabbit

参考文献：Schmutz J.,et al.Nature 431:268-274(2004).Aaltonen J.,et al.J. Clin. Endocrinol. Metab. 84:2744-2750(1999).Yamamoto N.,et al.J. Clin. Endocrinol. Metab. 87:2849-2856(2002).Yamamoto N.,et al.J. Clin. Endocrinol. Metab. 87:4495-4495(2002).McMahon H.E.,et al.Endocrinology 149:812-817(2008).

特异性：Human

别名：Growth/differentiation factor 9, GDF-9, GDF9

应用：ELISA (1:1000), IHC-P (10 μg/ml),

简单描述：Rabbit Polyclonal GDF9 / GDF-9 Antibody (aa45-59). Validated for use in WB, IHC-P, E.

详情：FunctionRequired for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.Cellular_LocationSecreted.Tissue_LocationExpressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level)

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

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