CD121b / IL1R2 Antibody | LBP64594 | Leading Biology

保存条件 ：Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

英文名 ：CD121b / IL1R2 Antibody

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：50 μg

商品分类：多克隆抗体

产品概述：Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

靶点/蛋白：Recombinant human IL-1R type II.

来源：Rabbit

参考文献：McMahan C.J.,et al.EMBO J. 10:2821-2832(1991).Liu C.,et al.J. Biol. Chem. 271:20965-20972(1996).Chou H.-H.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.Hillier L.W.,et al.Nature 434:724-731(2005).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

特异性：Human

别名：Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, IL1R2, IL1RB

应用：IHC-P (10 μg/ml)

简单描述：Rabbit Polyclonal CD121b / IL1R2 Antibody. Validated for use in WB, IHC-P, IF, E, IP.

详情：FunctionNon-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.Cellular_LocationIsoform Short: Secreted

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层