CDK3 Antibody (N-term Y19) | LBP60871 | Leading Biology

保存条件 ：Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

英文名 ：CDK3 Antibody (N-term Y19)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：400 μl

商品分类：多克隆抗体

产品概述：This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0.

靶点/蛋白：This CDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-38 amino acids from the N-terminal region of human CDK3.

来源：Rabbit

存储溶液：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

参考文献：Bullrich, F., et al., Cancer Res. 55(6):1199-1205 (1995).Meyerson, M., et al., EMBO J. 11(8):2909-2917 (1992).

特异性：Human

别名：Cyclin-dependent kinase 3, Cell division protein kinase 3, CDK3, CDKN3

应用：WB~~1:1000IHC-P~~1:50~100FC~~1:10~50

简单描述：Rabbit Polyclonal CDK3 Antibody (N-term Y19). Validated for use in WB, IHC-P, FC, E.

详情：FunctionSerine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner.Tissue_LocationExpressed in cancer cell lines and glioblastoma tissue.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层