Anti-CCT Theta Antibody, clone PK/13/72/8k | LM19963 | Leading Biology
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英文名 :Anti-CCT Theta Antibody, clone PK/13/72/8k
供应商 :安诺伦(北京)生物科技有限公司
商品分类:单克隆抗体靶点/蛋白:Rat anti-CCT theta antibody, clone PK/13/72/8k recognises the theta polypeptide of the CCT chaperonin molecule complex, also known as T-complex protein 1 subunit theta, CCT8 or CCTθ, a 547 amino acid ~:60kDa molecular chaperone.The intact CCT complex is composed of eight polypeptides in a double-ring structure. CCT is important within cells in aiding the folding of proteins including actin, tubulin and the VHL tumour suppressor protein.
来源:Rat
参考文献:1. Hynes, G. et al. (1996) Analysis of chaperonin-containing TCP-1 subunits in the human keratinocytetwo-dimensional protein database: further characterisation of antibodies toindividual subunits.Electrophoresis. 17: 1720-1727. 2. Llorca, O. et al. (2000) Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates inopen quasi-native conformations. EMBO J. 19: 5971-5979. 3. Hynes, G.M. Willison, K.R. (2000) Individual subunits of the eukaryotic cytosolic chaperonin mediate interactionswith binding sites located on subdomains of beta-actin.J Biol Chem. 275: 18985-18994. 4. Plimpton, R.L. et al. (2015) Structures of the Gβ-CCT and PhLP1-G&beta-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ? dimer assembly.Proc Natl Acad Sci U S A. 112 (8): 2413-8.
特异性:' + item.reactivity + '
别名:T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta, CCT8
简单描述:Rat Monoclonal Anti-CCT Theta Antibody, clone PK/13/72/8k . Validated for use in WB, IP. Clone: PK/13/72/8k.
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入驻年限:9年