USP9X Antibody (monoclonal) (M01) | LM18253 | Leading Biology

保存条件 ：存储于-20°C以下，避免反复冻融。

英文名 ：USP9X Antibody (monoclonal) (M01)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：100 μg

商品分类：单克隆抗体

产品概述：This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

靶点/蛋白：USP9X (NP_068706, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

来源：Mouse

存储溶液：Clear, colorless solution in phosphate buffered saline, pH 7.2.

参考文献：1.Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis.Wang B, Xie M, Li R, Owonikoko TK, Ramalingam SS, Khuri FR, Curran WJ, Wang Y, Deng XCell Death Differ. 2014 Apr 25. doi: 10.1038/cdd.2014.42.2.Deubiquitinase USP9x Confers Radioresistance through Stabilization of Mcl-1.Trivigno D, Essmann F, Huber SM, Rudner J.Neoplasia. 2012 Oct;14(10):893-904.3.Mcl-1 phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B-cells.Mazumder S, Choudhary GS, Al-Harbi S, Almasan A.Cancer Res. 2012 Apr 23.4.The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.Hepatology (2010) DOI: 10.1002/ hep.23836

特异性：Human

别名：Probable ubiquitin carboxyl-terminal hydrolase FAF-X, Deubiquitinating enzyme FAF-X, Fat facets in mammals, hFAM, Fat facets protein-related, X-linked, Ubiquitin thioesterase FAF-X, Ubiquitin-specific protease 9, X chromosome, Ubiquitin-specific-processing protease FAF-X, USP9X, DFFRX, FAM, USP9

应用：WB~~1:500~1000

简单描述：Mouse Monoclonal USP9X Antibody (monoclonal) (M01). Validated for use in WB, IF, E. Clone: 1C4.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层