CTH Antibody (monoclonal) (M03) | LM16776 | Leading Biology

保存条件 ：存储于-20°C以下，避免反复冻融。

英文名 ：CTH Antibody (monoclonal) (M03)

供应商 ：安诺伦（北京）生物科技有限公司

规格 ：100 μg

商品分类：单克隆抗体

产品概述：This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.

靶点/蛋白：CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

来源：mouse

存储溶液：Clear, colorless solution in phosphate buffered saline, pH 7.2.

参考文献：1.cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation.Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Zaid A, Giannogonas P, Cantalupo A, Dhayade S, Karalis KP, Wang R, Feil R, Cirino G.PLoS One. 2012;7(12):e53319. doi: 10.1371/journal.pone.0053319. Epub 2012 Dec 28.2.Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes.Zhang L, Yang G, Untereiner A, Ju Y, Wu L, Wang R.Endocrinology. 2013 Jan;154(1):114-26. doi: 10.1210/en.2012-1658. Epub 2012 Nov 26.3.An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries.Streeter E, Hart J, Badoer E.Naunyn Schmiedebergs Arch Pharmacol. 2012 Jul 17.4.Characterization of Hydrogen Sulfide and Its Synthases, Cystathionine ?]-Synthase and Cystathionine ?^-Lyase, in Human Prostatic Tissue and Cells.Guo H, Gai JW, Wang Y, Jin HF, Du JB, Jin J.Urology. 2012 Feb;79(2):483.e1-5.5.Glucocorticoids suppress cystathionine gamma-lyase expression and H(2)S production in lipopolysaccharide-treated macrophages.Zhu XY, Liu SJ, Liu YJ, Wang S, Ni X.Cell Mol Life Sci. 2010 Jan 10. [Epub ahead of print]6.H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels.Siebert N, Cantre D, Eipel C, Vollmar B.Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1266-73. Epub 2008 Oct 30.

特异性：Human, Mouse

别名：Cystathionine gamma-lyase, Cysteine-protein sulfhydrase, Gamma-cystathionase, CTH

应用：WB~~1:500~1000

简单描述：mouse Monoclonal CTH Antibody (monoclonal) (M03). Validated for use in WB, IHC, E. Clone: S51.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层