Anti-BCL2L11 Polyclonal Antibody

Anti-BCL2L11 Polyclonal Antibody

价格: ¥960 - 1600

品牌:江蓝纯

货号:K002607P

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库存 :99

供应商 :江蓝纯

规格 :50ul/100ul

英文名称 Rabbit BCL2L11 Polyclonal Antibody
别名 BSAS;HOX1;HOX1F
应用 IHC,IF
稀释比例 IHC1:50-1:100 IF1:50-1:100
交叉反应 Human
蛋白分子量 22kDa
Gene ID 10018
保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human BCL2L11
性状 Lyophilized or Liquid
Swiss Prot O43521
克隆类型 Polyclonal Antibody
来源 Rabbit
背景资料 The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

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