Recombinant Cavia porcellus  CTLA-4/CD152

英文名 ：Recombinant Cavia porcellus  CTLA-4/CD152

规格 ：10ug/50ug/500ug/1mg

Recombinant Cavia porcellus  CTLA-4/CD152  (CH92)

 

产品说明(Description)

Recombinant Cavia porcellus Cytotoxic T-lymphocyte protein 4  is produced by our Yeast expression system and the target gene encoding Ala37-Asp161 is expressed with a 6His tag at the C-terminus. 

Accession #: H0VUB1

Known as: Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4   

 

制剂(Formulation)

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

 

质量控制(Quality Control) 

Purity:           Greater than 90% as determined by reducing SDS-PAGE.    

Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

 

运输(Shipping)

The product is shipped on dry ice/polar packs. 
Upon receipt, store it immediately at the temperature listed below.

 

保存(Storage)

Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening. 
Please minimize freeze-thaw cycles.     

 

背景(Background)

Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

 

电泳(SDS-PAGE)

 

FOR RESEARCH USE ONLY