Recombinant Human FBPase 1/PFKFB1/PFK

价格： ￥1200 - 3520

品牌：近岸蛋白(Novoprotein) 品牌认证

货号：CI45

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英文名：Recombinant Human FBPase 1/PFKFB1/PFK

规格：10ug/50ug/500ug/1mg

Recombinant Human FBPase 1/PFKFB1/PFK (CI45)

产品说明(Description)

Recombinant Human 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Tyr471 is expressed with a 6His tag at the C-terminus.
Accession #: P16118
Known as: 6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 1; 6PF-2-K/Fru-2;6-P2ase liver isozyme; Fructose-2;6-bisphosphatase; PFKFB1; F6PK; PFRX

制剂（Formulation）
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5%Trehalose, 1mM EDTA, pH7.8.

质量控制（Quality Control）

Purity:      Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin:   Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

运输（Shipping）
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

保存（Storage）
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.

背景（Background）
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY