Recombinant Human Neuropeptide Y/NPY

英文名 ：Recombinant Human Neuropeptide Y/NPY

规格 ：10ug/50ug/500ug/1mg

Recombinant Human Neuropeptide Y/NPY  (C932)

 

产品说明(Description)

Recombinant Human Pro-Neuropeptide Y is produced by our Mammalian expression system and the target gene encoding Tyr29-Trp97 is expressed with a 6His tag at the C-terminus. 

Accession #: P01303

Known as: Pro-Neuropeptide Y; Neuropeptide Y; Neuropeptide Tyrosine; NPY; C-Flanking Peptide of NPY; CPON; NPY

 

制剂（Formulation）

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

 

质量控制（Quality Control） 

 

Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

 

复溶（Reconstitution）

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

 

保存（Storage）

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

 

背景（Background）

Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY can be cleaved into Neuropeptide Y and C-flanking peptide of NPY chain, which regulates energy usage, and it is involved in learning, memory processing, and epilepsy. NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. In addition, NPY increases the proportion of energy stored as fat and blocks nociceptive signals to the brain.

 

电泳(SDS-PAGE)

 

参考文献(Reference)

Neuropeptide Y increases differentiation of human olfactory receptor neurons through the Y1 receptor[J]. Tsung-Wei Huang. et al. Neuropeptides. 2019.

Different effects of neuropeptide Y on proliferation of vascular smooth muscle cells via regulation of Geminin[J]. Zhou-qin Jiang. et al. Molecular and Cellular Biochemistry. 2017.

Poly (ethylene-co-vinyl alcohol) is a suitable substrate for human olfactory neuroepithelial cell differentiation in vitro through a defined regulatory pathway[J]. Sheng-Tien Li. et al. Acta Biomaterialia. 2017.

 

 

 

FOR RESEARCH USE ONLY