Recombinant Human KLK7/Kallikrein 7

价格： ￥1200 - 3520

品牌：近岸蛋白(Novoprotein) 品牌认证

货号：C364

产品详情

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英文名：Recombinant Human KLK7/Kallikrein 7

规格：10ug/50ug/500ug/1mg

Recombinant Human KLK7/Kallikrein 7 (C364)

产品说明(Description)

Recombinant Human Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Glu23-His252 is expressed with a 6His tag at the C-terminus.
Accession #: AAH32005
Known as: Kallikrein-7; hK7; Serine Protease 6; Stratum Corneum Chymotryptic Enzyme; hSCCE; KLK7; PRSS6; SCCE

制剂（Formulation）
Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.

质量控制（Quality Control）

Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

运输（Shipping）
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

保存（Storage）
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.

背景（Background）
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY