Recombinant Human INHBC/NACGT1

英文名 ：Recombinant Human INHBC/NACGT1

规格 ：10ug/50ug/500ug/1mg

Recombinant Human INHBC/NACGT1  (C905)

 

产品说明(Description)

Recombinant Human Inhibin beta C Chain is produced by our Mammalian expression system and the target gene encoding Thr19-Ser352 is expressed with a 6His tag at the C-terminus. 

Accession #: P55103

Known as: Inhibin Beta C Chain; Activin Beta-C Chain; INHBC

 

制剂（Formulation）

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

 

质量控制（Quality Control） 

Purity:               Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin:        Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Bioactivity:   Immobilized Human INHBC-His (Cat#C905) at 0.5μg/ml (100 μl/well) can bind Human ACVR2A-Fc (Cat#CB60).

                          The ED50 of Human INHBC-His (Cat#C905) is 1-5 ug/ml .

 

复溶（Reconstitution）

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

 

保存（Storage）

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

 

背景（Background）

Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth and so on.

 

电泳(SDS-PAGE)

 

FOR RESEARCH USE ONLY