Recombinant Human Galectin-1/LGALS1

英文名 ：Recombinant Human Galectin-1/LGALS1

规格 ：10ug/50ug/500ug/1mg

Recombinant Human Galectin-1/LGALS1  (C285)

 

产品说明(Description)

Recombinant Human Galectin-1 is produced by our E.coli expression system and the target gene encoding Ala2-Asp135 is expressed with a 6His tag at the C-terminus. 

Accession #: P09382

Known as: Galectin-1; Gal-1; 14 kDa Laminin-Binding Protein; HLBP14; 14 kDa Lectin; Beta-Galactoside-Binding Lectin L-14-I; Galaptin; HBL; HPL; Lactose-Binding Lectin 1; Lectin Galactoside-Binding Soluble 1; Putative MAPK-Activating Protein PM12; S-Lac Lectin 1; LGALS1

 

制剂（Formulation）

Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM NaCl, 1mM DTT, pH 7.0.

 

质量控制（Quality Control） 

Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

 

复溶（Reconstitution）

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

 

保存（Storage）

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

 

背景（Background）

Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties.

 

电泳(SDS-PAGE)

 

参考文献(Reference)

Galectin-1 exhibits a protective effect against hepatotoxicity induced by dextran sulfate sodium in mice[J]. P Arda-Pirincci. et al.  Human and Experimental Toxicology. 2019.

Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin[J]. Sabrina Mai-Yi Fan. et al. Biomaterials. 2018.

 

 

FOR RESEARCH USE ONLY