Recombinant Human Arginase 1/ARG1/TINAGL1

英文名 ：Recombinant Human Arginase 1/ARG1/TINAGL1

规格 ：10ug/50ug/500ug/1mg

Recombinant Human Arginase 1/ARG1/TINAGL1  (CP77)

 

产品说明(Description)

Recombinant Human Arginase-1 is produced by our Mammalian expression system and the target gene encoding Met1-Lys322 is expressed with a 6His tag at the C-terminus. 

Accession #: P05089

Known as: Arginase-1; Liver-type arginase; Type I arginase; ARG1

 

制剂（Formulation）

Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mMNaCl, 20%Glycerol,1mMDTT,pH7.4.

 

质量控制（Quality Control） 

Purity:            Greater than 90% as determined by reducing SDS-PAGE.    

Endotoxin:     Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Bioactivity:    Measured by the production of urea during the hydrolysis of arginine. The specific activity is 46411 pmol/min/µg.

 

 

运输(Shipping)

The product is shipped on dry ice/polar packs. 
Upon receipt, store it immediately at the temperature listed below.

 

保存(Storage)

Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening. 
Please minimize freeze-thaw cycles.     

 

背景（Background）

ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle, while it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.

 

电泳(SDS-PAGE)

 

FOR RESEARCH USE ONLY