盐酸四环素 USP级

保质期 ：两年

英文名 ：Tetracycline hydrochloride

库存 ：99

供应商 ：江蓝纯

CAS号 ：64-75-5

规格 ：25g/100g

属性

敏感性	对光及空气敏感
密度	1.1770
熔点	223°C
存贮条件	储存温度-20°C

描述

产品介绍	溶解度:20 g/L水，5 g/L乙醇，不溶于醚、烃类和丙酮。
别名	盐酸四环素 ;
生化机理	Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action. Mode of Resistance: The effects are inactivated via a loss of cell wall permeability. Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.
应用	作用模式: 靠阻止胺酰基-tRNA至核糖体30S亚单位上阻止蛋白的合成。 抗菌谱:革兰氏阴性和阳性细菌。 阻断模式: 细胞壁渗透性缺失。