北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价价格

保存条件：冷藏

保质期：长期

英文名：Recombinant Mouse Granulocyte-Macrophage Colony-Stimulating Factor

库存：960

供应商：北京百奥莱博科技有限公司

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价
规格：10μg|50μg|500μg|1mg
产地：国产|进口
品牌：百奥莱博
编号：JN1353
英文名：Recombinant Mouse Granulocyte-Macrophage Colony-Stimulating Factor
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala18-Lys141在C端含有His标签。

GM-CSF质量控制：＞95%(还原性SDS-PAGE)

GM-CSF制剂：冻干品

GM-CSF保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

GM-CSF复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于GM-CSF：
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.

北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价正在火爆热销，除此之外，为您推荐下别热销产品：

·重组人LAIR1(白细胞相关免疫球蛋白样受体1)
编号：JN1678
英文名称：Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln22-His163在C端含有His标签。

LAIR1质量控制：＞95%(还原性SDS-PAGE)

LAIR1制剂：冻干品

LAIR1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LAIR1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LAIR1：
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells, highly in naive T-cells and B-cells. As an inhibitory receptor, LAIR1 plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. LAIR1 plays inhibitory role independently of SH2-containing phosphatases and modulates cytokine production in CD4+ T-cells. It down-regulates IL2 and IFNG production while inducing secretion of transforming growth factor beta, also down-regulates IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. LAIR1 inhibits the differentiation of peripheral blood precursors towards dendritic cells. It also restrains proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells.

北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价关键词：重组小鼠GM-CSF蛋白,JN1353,重组GM-CSF,重组小鼠粒细胞-巨噬细胞集落刺激因子

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北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价关键词：重组小鼠GM-CSF蛋白,JN1353,重组GM-CSF,重组小鼠粒细胞-巨噬细胞集落刺激因子

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北京重组小鼠GM-CSF(粒细胞-巨噬细胞集落刺激因子)报价