文献支持AMACR Monoclonal Antibody_货号:E-AB-22010_单克隆抗体

Verified Samples in WB:HepG2,Mouse kidney
Verified Samples in IHC:Human stomach
Verified Samples in IF:Mouse kidney

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300

Monoclonal

IgG

Synthetic Peptide

AMACR

2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha-methylacyl-CoA racemase;Amacr;AMACR;AMACRD;CBAS4;EC 5.1.99.4;Macr1;RACE;RM抗体

Q9UHK6

42kDa

42kDa

Peroxisome. Mitochondrion.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Protein A purification

Cell Biology; Metabolism; Signal Transduction

Clone:1F1

Unconjugated

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.