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保存条件 :-20oC
库存 :大量
保质期 :1年以上
CAS号 :无
供应商 :PeproTech(派普泰克)
英文名 :Recombinant Murine IFN-gamma
Synonyms : |
Immune Interferon, type II interferon, T cell interferon, MAF |
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Description : |
IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues. |
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Catalog #: |
315-05 |
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Source : |
E.coli |
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Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin Level : |
Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
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Biological Activity : |
Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED 50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. |
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Selected References : |
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AA Sequence : |
MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC |
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PubMed Link : |
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Country of Origin : |
USA |
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Special Sizes: |
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Usage: |
派普泰克生物科技(苏州)有限公司(PeproTech中国)
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入驻年限:15年