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库存 :大量
供应商 :PeproTech(派普泰克)
CAS号 :无
英文名 :Recombinant Human GM-CSF
保质期 :1年以上
保存条件 :-20oC
PeproTech为研发机构提供高质量的科研产品,支持病毒研究及治疗性抗体开发,共同努力 打赢这场新型冠状病毒狙击战。 |
用途/可能作用机制:DC疫苗的研发 |
Synonyms : |
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha |
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Description : |
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. Manufactured using all non-animal reagents. |
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Catalog #: |
AF-300-03 |
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Source : |
E.coli |
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Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin Level : |
Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
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Biological Activity : |
The ED 50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. |
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AA Sequence : |
MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE |
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PubMed Link : |
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Country of Origin : |
USA |
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Special Sizes: |
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Usage: |
派普泰克生物科技(苏州)有限公司(PeproTech中国)
品牌商实名认证
钻石会员
入驻年限:15年