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保质期 :1年以上
英文名 :Recombinant Human IL-6
库存 :大量
供应商 :PeproTech(派普泰克)
CAS号 :无
保存条件 :-20oC
PeproTech为研发机构提供高质量的科研产品,支持病毒研究及治疗性抗体开发,共同努力 打赢这场新型冠状病毒狙击战。 |
用途/可能作用机制:DC疫苗的研发 |
Synonyms : |
26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 |
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Description : |
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Manufactured using all non-animal reagents. |
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Catalog #: |
AF-200-06 |
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Source : |
E.coli |
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Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin Level : |
Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
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Biological Activity : |
The ED 50 was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. |
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AA Sequence : |
PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM |
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PubMed Link : |
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Country of Origin : |
USA |
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Special Sizes: |
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Usage: |
PeproTech重组人IL-6 (Animal Free)参考文献链接:
http://www.peprotech.com/en-US/Pages/References/AF-200-06
PeproTech重组人IL-6 (Animal Free)参考文献链接:
http://www.peprotech.com/en-US/Pages/References/AF-200-06
派普泰克生物科技(苏州)有限公司(PeproTech中国)
品牌商实名认证
钻石会员
入驻年限:15年