TIRAP Antibody (OASG07203)

抗体英文名 ：TIRAP Antibody (OASG07203)

靶点 ：TIRAP

应用范围 ：IHC, ELISA

宿主 ：Rabbit

适应物种 ：Human, Mouse

克隆性 ：Polyclonal

保存条件 ：Store at -20C. Avoid repeated freeze/thaw cycles.

形态 ：Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

亚型 ：IgG

免疫原 ：Synthesized peptide derived from human TIRAP around the non-phosphorylation site of Y86. Location: 30-110aa.

规格 ：100 uL

NCBI Gene Id: 114609; 117149;
Swissprot Id: P58753
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OASG07203