CASR Antibody (OASG01066)

抗体英文名 ：CASR Antibody (OASG01066)

靶点 ：CASR

应用范围 ：WB, IHC, ELISA

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat

克隆性 ：Polyclonal

保存条件 ：Store at -20C. Avoid repeated freeze/thaw cycles.

形态 ：Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

亚型 ：IgG

免疫原 ：Synthesized peptide derived from human CaSR around the non-phosphorylation site of T888. Location: 830-910aa.

规格 ：100 uL

NCBI Gene Id: 846; 12374; 24247
Swissprot Id: P41180
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OASG01066