BAND 3 Antibody (OABB01920)

抗体英文名 ：BAND 3 Antibody (OABB01920)

靶点 ：BAND 3

应用范围 ：WB, IHC-P, IHC-F

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat

克隆性 ：Polyclonal

保存条件 ：Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml. +4C

形态 ：Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

亚型 ：IgG

免疫原 ：E. coli-derived human Band 3 (Position: E28-N365). Human Band 3 shares 75.7% and 74.5% amino acid (aa) sequence identity with mouse and rat Band 3, respectively.

规格 ：100 ug

NCBI Gene Id: 6521
Swissprot Id: P02730
Band 3 is also known as SLC4A1. The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. The encoded protein associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of the exchanger. This protein is predominantly dimeric but forms tetramers in the presence of ankyrin. Many mutations in this gene are known in man, and these mutations can lead to two types of disease: destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABB01920

Human Placenta Tissue

Anti-Band 3 Picoband antibody, OABB01920, IHC(P)
IHC(P): Human Placenta Tissue

Human Placenta Tissue

Anti-Band 3 Picoband antibody, OABB01920, IHC(F)
IHC(F): Human Placenta Tissue

Mouse Kidney Tissue

Anti-Band 3 Picoband antibody, OABB01920, IHC(P)
IHC(P): Mouse Kidney Tissue

Rat Kidney Tissue

Anti-Band 3 Picoband antibody, OABB01920, IHC(P)
IHC(P): Rat Kidney Tissue

Rat Brain Tissue Lysate, Rat Kidney Tissue Lysate, Rat Liver Tissue Lysate, Rat Spleen Tissue Lysate, Human Placenta Tissue Lysate

Anti-Band 3 Picoband antibody, OABB01920, Western blotting
All lanes: Anti Band 3 (OABB01920) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Rat Kidney Tissue Lysate at 50ug
Lane 3: Rat Liver Tissue Lysate at 50ug
Lane 4: Rat Spleen Tissue Lysate at 50ug
Lane 5: Human Placenta Tissue Lysate at 50ug
Predicted bind size: 102KD
Observed bind size: 102KD