MCL1 Antibody (Phospho-Ser159/Thr163) (OABF01204)

抗体英文名 ：MCL1 Antibody (Phospho-Ser159/Thr163) (OABF01204)

靶点 ：MCL1

应用范围 ：WB, IHC-P

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat

标记物 ：Unconjugated

克隆性 ：Polyclonal

保存条件 ：Store at -20C for 12 months.

形态 ：Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

亚型 ：IgG

免疫原 ：KLH conjugated synthetic phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163. Immunogen range: 140-190/350.

规格 ：100 ul

NCBI Gene Id: 4170
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABF01204

Rat brain

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Phospho-Mcl1 (Ser159/Thr163) Polyclonal Antibody, Unconjugated (OABF01204) at 1:200, followed by conjugation to the secondary antibody and DAB staining