Anti-MEK1 (E203K) Mouse Monoclonal Antibody点突变抗体

价格： ￥4800

品牌：N&T Biosciences

货号：26268

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抗体名：MEK1(E203K) 抗体

抗体英文名：MEK1(E203K) Antibody

靶点：MAP2K1; MAPKK1; MEK1; MKK1; PRKMK1

浓度：1mg/ml

应用范围：ELISA,WB

宿主：Mouse

适应物种：颈椎动物

保质期：2年

抗原来源：Mouse

目录编号：26268

级别：试验级

库存：300000

供应商：NewEastBio

标记物：FITC

克隆性：单克隆

保存条件：-20℃

形态：液体

亚型：IgG

免疫原：A synthetic peptide from the internal region of MEK1 which includes the mutation of E203K, human origin.

规格：100μl

MEK1 (E203K) [26268]
[100ul]

Catalog Number: 26268

Gene Symbol: MAP2K1; MAPKK1; MEK1; MKK1; PRKMK1

Description: Anti-MEK1 (E203K) Mouse Monoclonal Antibody

Background: MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK3/ERK1 and MAPK1/ERK2, thus activates the MAP pathway and regulates transcription. Abnormal of the MEK1 protein, including point mutations, are implicated in diseases such as cardiofaciocutaneous syndrome (CFC) and melanoma.

Immunogen: A synthetic peptide from the internal region of MEK1 which includes the mutation of E203K, human origin.

Applications: ELISA,WB

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes E203K mutant, but not wild-type MEK1 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Download Datasheet:

Western blot:

Western blot analysis of recombinant MEK1 (E203K) and wildtype proteins. Purified His-tagged MEK1 (E203K) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with anti-MEK1 (E203K) monoclonal antibody (Cat. #26268).