Anti NOTCH1 (M2011R) Mouse Monoclonal Antibody点突变抗体

价格： ￥4800

品牌：纽斯特生物

货号：26444

产品详情

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免疫原： A synthetic peptide from the internal region of NOTCH1 which includes the mutation of M2011R, human origin.

亚型：IgG

形态：液体

保存条件：-20℃

克隆性：单克隆

标记物：FITC

保质期：两年

抗原来源：Mouse

目录编号：26444

级别：实验级

库存：30000

供应商：武汉纽斯特生物技术有限公司

宿主：Mouse

应用范围：ELISA、WB、IF、IHC

浓度：1 mg/ml

靶点：NOTCH1、AOS5、AOVD1、TAN1、hN1

抗体英文名：NOTCH1(M2011R) Antibody

抗体名：NOTCH1(M2011R)

规格：100μl

NOTCH1 (M2011R) [26444]
[100ul]

Catalog Number: 26444

Gene Symbol: NOTCH1, AOS5, AOVD1,TAN1, hN1

Description: Anti-NOTCH1 (M2011R) Mouse Monoclonal Antibody

Background: NOTCH1 is a human gene encoding a single-pass transmembrane receptor. It is a member of the NOTCH family. NOTCH family members play a role in a variety of developmental processes by controlling cell fate decisions. Diseases associated with NOTCH1 include aortic valve disease 1 and adams-oliver syndrome 5, and so on. An important paralog of this gene is NOTCH2.

Immunogen: A synthetic peptide from the internal region of NOTCH1 which includes the mutation of M2011R, human origin.

Applications: ELISA, WB, IF, IHC

Recommended Dilutions:
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IF: 1:50-1:100
IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes M2011R mutant, but not wild-type NOTCH1 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Western blot:

Western blot analysis of recombinant NOTCH1 (M2011R) and wildtype proteins. Purified His-tagged NOTCH1 (M2011R) protein (lane1) and corresponding wild-type protein (lane2) were blotted with anti-NOTCH1 (M2011R) monoclonal antibody (Cat. #26444).

Immunofluorescence:

Immunofluorescence of cells expressing NOTCH1 proteins with anti-NOTCH1 (M2011R) antibody. HEK293T cells were transfected with pCDNA3-GFP-NOTCH1 (WT) plasmid (left column) or pCDNA3-GFP-NOTCH1 (M2011R) plasmid (right column), then fixed and stained with anti-NOTCH1 (M2011R) monoclonal antibody (Cat. #26444).