Anti-ATM (R2443Q) Mouse Monoclonal Antibody点突变

价格： ￥4800

品牌：纽斯特

货号：26143

产品详情

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免疫原：A synthetic peptide from the internal region of ATM which includes the mutation of R2443Q, human origin.

亚型：IgG

形态：液体

保存条件：-20℃

克隆性：单克隆

标记物：FITC

适应物种：脊椎动物

保质期：两年

抗原来源：Mouse

目录编号：26143

级别：实验级

库存：30000

供应商：武汉纽斯特生物技术有限公司

宿主：Mouse

应用范围：ELISA, WB, IHC

浓度：1mg/ml

靶点：ATM

抗体英文名：ATM (R2443Q)antibody

抗体名：ATM (R2443Q）抗体

规格：100μl

ATM (R2443Q) [26143]
[100 µL]

Catalog Number: 26143

Gene Symbol: ATM

Description: Anti-ATM (R2443Q) Mouse Monoclonal Antibody

Background: Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.

Immunogen: A synthetic peptide from the internal region of ATM which includes the mutation of R2443Q, human origin.

Applications: ELISA, WB, IHC

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes ATM (R2443Q), but not wild type ATM protein from vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Western blot:

Western blot analysis of recombinant ATM (R2443Q) and wildtype proteins. Purified His-tagged ATM (R2443Q) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ATM (R2443Q) mouse monoclonal antibody (Cat. #26143).