Anti-Active Rab4 Mouse Monoclonal Antibody活性抗体

Anti-Active Rab4 Mouse Monoclonal Antibody活性抗体

价格: ¥4800

品牌:纽斯特生物(New EastBiosciences)

货号:26921

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免疫原 :Mouse

亚型 :IgG

形态 :液体

保存条件 :-20℃

克隆性 :单克隆

标记物 :FITC

适应物种 :脊椎动物

保质期 :两年

抗原来源 :Mouse

目录编号 :26921

级别 :实验级

库存 :30000

供应商 :武汉纽斯特生物技术有限公司

宿主 :Mouse

应用范围 :IP、IHC

浓度 :1mg/ml

靶点 :Rab4

抗体英文名 :Rab4—GTP

抗体名 :Rab4

规格 :30μl

Active Rab4-GTP [NL26921]
[30 µL]
Catalog Number: NL 26921
Gene Symbol: RAB4
Description: Anti-Active Rab4 Mouse Monoclonal Antibody
Background: Rab-4 belongs to the small GTPase Rab family. It interacts with RAB11FIP1, RABEP1, ZFYVE20, RUFY1, SGSM1, SGSM2 and SGSM3. It participates in protein transport and in vesicular traffic.
Immunogen: Recombinant full length protein of active Rab4A.
Applications: IP, IHC
Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP
1:50~100 dilution for IHC
Concentration: 1 mg/ml
Host: mouse
Format: Liquid
Clonality: Monoclonal
Isotype: IgG
Purity: Purified from ascites
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti-active Rab4 antibody recognizes active Rab4 from vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
Immunoprecipitation/Western blot:
Rab4A activation assay. Purified GST-tagged Rab4A proteins (Cat. #10130) were immunoprecipitated with the anti-active Rab4 monoclonal antibody (Cat. No. 26921) after treated with GDP (lane 1) or GTPγ S(lane 2), and was blotted with anti-Rab4A polyclonal antibody (Cat. No. 21067). Input control is shown in the bottom panel.
Publications:
1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
Hepatology Volume 61, Issue 1, pages 361–374, January 2015
2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
Endocrinology. 2014 Sep;155(9):3315-28

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入驻年限:8年

联系人:黄先生

地址:武汉

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