Anti-Active Rab3 Mouse Monoclonal Antibody活性抗体

价格： ￥4800

品牌：纽斯特生物（New EastBiosciences)

货号：26920

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免疫原：Mouse

亚型：IgG

形态：液体

保存条件：-20℃

克隆性：单克隆

标记物：FITC

适应物种：脊椎动物

保质期：两年

抗原来源：Mouse

目录编号：26920

级别：实验级

库存：30000

供应商：武汉纽斯特生物技术有限公司

宿主：Mouse

应用范围：IP、IHC、IF

浓度：1mg/ml

靶点：Rab3

抗体英文名：Rab3-GTP antibody

抗体名：Rab3

规格：30μl

Active Rab3-GTP [NL26920]
[30 µL]

Catalog Number: NL26920

Gene Symbol: RAB3

Description: Anti-Active Rab3 Mouse Monoclonal Antibody

Background: Rab3 is a member of the Rab-family GTPases and is specifically targeted to synaptic vesicles.

Immunogen: Recombinant full length protein of active Rab3A

Applications: IP, IHC, IF

Recommended Dilutions:
1 µg for ~2 mg total cellular proteins for IP
1:100 dilution for IHC, IF

Concentration: 1 mg/ml

Host: mouse

Format: Liquid

Clonality: Monoclonal

Isotype: IgG

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Anti-active Rab3 antibody recognizes active Rab3 proteins of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Immunoprecipitation/Western blot:

Rab3 activation assay. Purified full-length Rab3A proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti-active Rab3 monoclonal antibody (Cat. No. 26920). Immunoblot was with an anti-Rab3A polyclonal antibody (Cat. No. 21041).

Publications:

1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
Hepatology Volume 61, Issue 1, pages 361–374, January 2015

2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
Endocrinology. 2014 Sep;155(9):3315-28