Anti-Active Rab11 Mouse Monoclonal Antibody活性抗体

Anti-Active Rab11 Mouse Monoclonal Antibody活性抗体

价格: ¥4800

品牌:纽斯特生物(New EastBiosciences)

货号:26919

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免疫原 :Mouse

亚型 :IgG

形态 :液体

保存条件 :-20℃

克隆性 :单克隆

标记物 :FITC

适应物种 :脊椎动物

保质期 :两年

抗原来源 :Mouse

目录编号 :26919

级别 :实验级

库存 :30000

供应商 :武汉纽斯特生物技术有限公司

宿主 :Mouse

应用范围 :IP、IHC

浓度 :1mg/ml

靶点 :Rab11

抗体英文名 :Rab11-GTP antibody

抗体名 :Rab11

规格 :30μl

Active Rab11-GTP [NL26919]
[30 µL]
Catalog Number: NL26919
Gene Symbol: RAB11
Description: Anti-Active Rab11 Mouse Monoclonal Antibody
Background: Small GTPases of the Rab-family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome.
Immunogen: Recombinant full length protein of active Rab11
Applications: IP, IHC
Recommended Dilutions: IP: 1 μg for 1~2 mg total cellular proteins
IHC: 1:50~100 dilution
Concentration: 1 mg/ml
Host: mouse
Format: Liquid
Clonality: Monoclonal
Isotype: IgG2b
Purity: Purified from ascites
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti-active Rab11 antibody recognizes active Rab11 from vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
Immunoprecipitation/Western blot:
Purified full-length Rab11 proteins were immunoprecipitated after treated with GDP (lane left) or GTPγS (lane right). Immunoprecipitation was done with the anti-active Rab11 monoclonal antibody (Cat. No. 26919). Immunoblot was with an anti-Rab5 polyclonal antibody (Cat. No. 21157).
Publications:
1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
Hepatology Volume 61, Issue 1, pages 361–374, January 2015
2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
Endocrinology. 2014 Sep;155(9):3315-28

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