Anti-active Gas Mouse Monoclonal Antibody活性抗体

价格： ￥4800

品牌：纽斯特生物（New EastBiosciences)

货号：26906

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免疫原：Mouse

亚型：IgG

形态：液体

保存条件：-20℃

克隆性：多克隆

标记物：FITC

适应物种：Mouse

保质期：两年

抗原来源：Mouse

目录编号：26906

级别：实验级

库存：3000

供应商：NewEastBio

宿主：Mouse

应用范围： IP、 IHC

浓度：1mg/ml

靶点：Gas

抗体英文名：Gas antibody

抗体名：Gas

规格：30μl

Active Gαs-GTP [NL26906]
[30 µL]

Catalog Number: NL26906

Gene Symbol: Gnas

Description: Anti-Active Gα_s-GTP Mouse Monoclonal Antibody

Background: Heterotrimeric G proteins are critical cellular signal transducers. Gα_srepresents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases.

Immunogen: Recombinant full length protein of active Gα_s

Applications: IP, IHC

Recommended Dilutions: 1 µg for 1~2 mg total cellular proteins for IP;
1:100 dilution for IHC

Concentration: 1 mg/ml

Host: mouse

Format: Liquid

Clonality: Monoclonal

Isotype: IgG

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Anti-active Gα_s antibody recognizes active Gα_s of vertebrates

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Immunoprecipitation/Western blot:

Gα_s activation assay. Purified Gα_s proteins were loaded as a control (lanes 1) or immunoprecipitated after treated with GDP (lane 2) or GTPγS (lane 3). Immunoprecipitation was done with the anti-active Gα_s monoclonal antibody (Cat. No. 26906). Immunoblot was with an anti- Gα_s monoclonal antibody (Cat. No. 26006).

Publications:

1. Glucocorticoid acts on a putative G protein-coupled receptor to rapidly regulate the activity of NMDA receptors in hippocampal neurons
Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E747-582. CRH activation of different signaling pathways results in differential calcium signaling in human pregnant myometrium before and during labor
J Clin Endocrinol Metab. 2012 Oct;97(10):E1851-613. Estrogenic action on arterial smooth muscle: permissive for maintenance of CRHR2 expression
Endocrinology. 2012 Apr;153(4):1915-244. Corticotropin-releasing hormone stimulates mitotic kinesin-like protein 1 expression via a PLC/PKC-dependent signaling pathway in hippocampal neurons
Mol Cell Endocrinol. 2012 Oct 15;362(1-2):157-645. Rapid actions of xenoestrogens disrupt normal estrogenic signaling
Steroids Volume 81, March 2014, Pages 36–426. Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation
Hum. Mol. Genet. (2014)