CUDC-101

保存条件 ：-20°C

保质期 ：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3097℃ for several months.

英文名 ：CUDC-101

库存 ：详询

供应商 ：详询

CAS号 ：1012054-59-9

规格 ：2mg/10mg/25mg/50mg/1mL/10mM

ID：T3108

PURITY：0.98

Formula：C24H26N4O4

MolWt：434.49

Appearance：白色粉末

Solubility：G4DMSO：20 mg/mL (46.03 mM)

Bioactivity：CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.

Status：

Pathways：Chromatin/Epigenetic

Target：HDAC inhibitor

Receptor：EGFR , HDAC , HDAC1 , HDAC6 , HDAC3