Alvelestat (AZD9668)

保存条件 ：-20°C

保质期 ：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3096℃ for several months.

英文名 ：Alvelestat (AZD9668)

库存 ：详询

供应商 ：详询

CAS号 ：848141-11-7

规格 ：2mg/5mg/10mg/25mg/50mg/1mL/10mM

ID：T3107

PURITY：0.98

Formula：C25H22F3N5O4S

MolWt：545.53

Appearance：白色粉末

Solubility：G4Soluble in DMSO > 10 mM

Bioactivity：Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. Phase 2.

Status：

Pathways：Protease/Proteasome

Target：Serine Protease inhibitor

Receptor：neutrophil elastase