GSK1838705A

保存条件 ：-20°C

保质期 ：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3077℃ for several months.

英文名 ：GSK1838705A

库存 ：详询

供应商 ：详询

CAS号 ：1116235-97-2

规格 ：2mg/5mg/10mg/25mg/50mg/1ml/10mM

ID：T3079

PURITY：1

Formula：C27H29FN8O3

MolWt：532.57

Appearance：土黄色色粉末

Solubility：G4DMSO >107mg/mL; Water <1mg/mL

Bioactivity：GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.

Status：Undetermined activity

Pathways：Tyrosine Kinase/Adaptors

Target：TGF-beta/Smad inhibitor; IGF-1R inhibitor

Receptor：ALK/insulin receptor/IGF-1R/RSK1