Stem Cell Signaling PCR Array 干细胞信号转导基因表达PCR芯片

干细胞信号转导基因表达PCR芯片可以同时检测参与胚胎干细胞（ESC）及诱导多能干细胞（IPSC）维护和分化的信号转导通路的84个关键基因的表达。该芯片包含参与多能干细胞维持和分化的主要信号转导通路的受体和转录因子，包括成纤维细胞生长因子（bFGF）、Hedgehog、Notch、TGF和WNT。利用实时定量 PCR，研究者可以方便并且可信地对与干细胞维护和分化相关的基因进行同时检测。
Pluripotency Maintenance Pathway: Receptors: IL6ST (GP130), LIFR.
Transcription Factor: STAT3.
Fibroblast Growth Factor (FGF) Signaling Pathway: Receptors: FGFR1, FGFR2, FGFR3, FGFR4. Transcription Factor: CDX2.
Hedgehog Signaling Pathway: Receptors & Co-Receptors: PTCH1, PTCHD2, SMO.
Transcription Factors & Co-Factors: GLI1, GLI2, GLI3, SUFU.
Notch Signaling Pathway: Receptors & Co-Receptors: NCSTN, NOTCH1, NOTCH2, NOTCH3, NOTCH4, PSENEN, PSEN1, PSEN2.
Transcription Factor: RBPJL.
TGFβ Superfamily Signaling Pathway: Receptors & Co-Receptors: ACVRL1, ACVR1, ACVR1B, ACVR1C, ACVR2A, ACVR2B, AMHR2, BMPR1A, BMPR1B, BMPR2, ENG, LTBP1, LTBP2, LTBP3, LTBP4, RGMA, TGFBR1, TGFBR2, TGFBR3, TGFBRAP1.
Transcription Factors & Co-Factors: EP300, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6, SMAD7, SMAD9, CREBBP, E2F5, RBL1, RBL2, SP1, ZEB2.
Wnt Signaling Pathway: Receptors: FZD1, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9, LRP5, LRP6, VANGL2.
Transcription Factors & Co-Factors: BCL9, BCL9L, CTNNB1, LEF1, NFAT5, NFATC1, NFATC2, NFATC3, NFATC4, PYGO2, TCF7L1, TCF7L2, TCF7.