Glycosylation PCR Array 糖基化基因表达PCR芯片

糖基化基因表达PCR芯片可用于研究编码关键酶的84个基因的表达，这些酶在翻译后，自蛋白多糖和糖蛋白添加和移除糖残基。芯片包含几个重要的糖基转移酶和糖苷酶基因，包括半乳糖，葡萄糖，甘露糖， N-乙酰葡糖胺，N-乙酰基半乳糖胺，岩藻糖和唾液酸。其中一些代表性的酶同时作用于鞘糖脂。使用该芯片试剂盒及配套试剂检测RNA实验标本，研究者可以简单准确的检测和分析蛋白糖基化相关的基因表达。
N-acetylgalactosaminyltransferases: GALNT1, GALNT10, GALNT11, GALNT12, GALNT13, GALNT14, GALNT2, GALNT3, GALNT4, GALNT6, GALNT7, GALNT8, GALNT9, GALNTL1, GALNTL5, GALNTL6.
N-acetylglucosaminyltransferases: A4GNT, B3GNT2, B3GNT3, B3GNT4, B3GNT8, GCNT1, GCNT3, GCNT4, MGAT1, MGAT2, MGAT3, MGAT4A, MGAT4B, MGAT4C, MGAT5, MGAT5B, OGT,
POMGNT1.
Galactosyltransferases: B3GALTL, B4GALT1, B4GALT2, B4GALT3, B4GALT5, C1GALT1.
Glucosyltransferases: UGGT1, UGGT2.
Mannosidases: EDEM1, EDEM2, EDEM3, MAN1A1, MAN1A2, MAN1B1, MAN1C1, MAN2A1, MAN2A2, MAN2B1, MANBA.
Mannosyltransferases: POMT1, POMT2.
Galactosides & Glucosidases & Hexosaminidases: GANAB, GLB1, HEXA, HEXB, MOGS, PRKCSH.
Fucosidases & Fucosyltransferases: FUCA1, FUCA2, FUT11, FUT8, POFUT1, POFUT2.
Sialidases: NEU1, NEU2, NEU3, NEU4.
Sialyltransferases: ST3GAL1, ST3GAL2, ST6GAL1, ST6GALNAC1, ST8SIA2, ST8SIA3, ST8SIA4, ST8SIA6.
Mannose-6-Phosphate Synthesis & Catabolism: GNPTAB, GNPTG, NAGPA.
Others: AGA, C1GALT1C1.
N-Linked Glycosylation: AGA, B3GNT2, B3GNT3, B3GNT8, B4GALT1, B4GALT2, B4GALT3, EDEM1, EDEM2, EDEM3, FUCA1, FUCA2, FUT11, FUT8, GANAB, GLB1, GNPTAB, GNPTG, HEXA, HEXB, MAN1A1, MAN1A2, MAN1B1, MAN1C1, MAN2A1, MAN2A2, MAN2B1, MANBA, MGAT1, MGAT2, MGAT3, MGAT4A, MGAT4B, MGAT4C, MGAT5, MGAT5B, MOGS, NAGPA, NEU1, NEU2, NEU3, NEU4, PRKCSH, ST6GAL1, ST8SIA2, ST8SIA3, ST8SIA4, ST8SIA6, UGGT1, UGGT2.
O-Linked Glycosylation: A4GNT, B3GALTL, B3GNT8, B4GALT5, C1GALT1, C1GALT1C1, GALNT1, GALNT10, GALNT11, GALNT12, GALNT13, GALNT14, GALNT2, GALNT3, GALNT4, GALNT6, GALNT7, GALNT8, GALNT9, GALNTL1, GALNTL5, GALNTL6, GCNT1, GCNT3, GCNT4, OGT, POFUT1, POFUT2, POMGNT1, POMT1, POMT2, ST3GAL1, ST3GAL2, ST6GALNAC1, ST8SIA3, ST8SIA6.
Glycosphingolipids: B3GNT3, B3GNT4, B4GALT1, B4GALT2, B4GALT3, GLB1, HEXA, HEXB, ST3GAL1, ST3GAL2, ST8SIA6.